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The Effects of Vitamin B in Depression

[ Vol. 23 , Issue. 38 ]


Kathleen Mikkelsen, Lily Stojanovska and Vasso Apostolopoulos   Pages 4317 - 4337 ( 21 )


Vitamins are dietary components which are necessary for life. They play a major role in health and their deficiency may be linked to symptoms of psychiatric disorders. B vitamins are required for proper functioning of the methylation cycle, monoamine oxidase production, DNA synthesis and the repair and maintenance of phospholipids. Vitamin B deficiency could influence memory function, cognitive impairment and dementia. In particular, vitamins B1, B3, B6, B9 and B12 are essential for neuronal function and deficiencies have been linked to depression. We discuss the causes of depression and the neurochemical pathways in depression. In particular, we provide evidence that vitamin B contributes to the complexity of depressive symptoms.


Depression, vitamin B, vitamin B6, vitamin B12, vitamin B complex.


Centre for Chronic Disease, College of Health and Biomedicine, Victoria University, Melbourne, VIC Australia.

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