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Recent Developments of Phototherapy Based on Graphene Family Nanomaterials

[ Vol. 24 , Issue. 3 ]

Author(s):

Baomei Zhang, Yang Wang, Jiyong Liu and Guangxi Zhai   Pages 268 - 291 ( 24 )

Abstract:


Graphene-based nanomaterials have drawn abundant interest in various fields such as biomedicine in recent years. Thanks to the ultra-high surface area of single-layered graphene, higher molecular loading is obtained. In addition, easy modifications were acquired because of its ample oxygen-content functional groups. Owing to its excellent physical– chemical properties, graphene-based nanomaterials have been widely explored as novel nanovectors for disease theranostics. In this article, we gave a comprehensive review of graphenebased nanomaterials, including introduction about different members of graphene family nanomaterials (GFNs), various modifications, toxicity and biomedical applications of graphene- based derivatives. More attentions were given to phototherapy in this paper. The mechanisms of photothermal and photodynamic therapy were also offered. Finally, the prospects and challenges of the graphene-based nanomaterials were discussed in this review.

Keywords:

GFNs, modifications, toxicity, biomedical applications, phototherapy, multifunctional nanoformulations.

Affiliation:

Department of Pharmacy, Changhai Hospital, Second Military Medical University, Shanghai 200433,, Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012



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