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Editorial: Research and Selection of Multitarget Compounds in Medicinal Chemistry

[ Vol. 24 , Issue. 16 ]

Author(s):

Luciana Scotti, Francisco Jaime Bezerra Mendonça and Marcus T. Scotti   Pages 1627 - 1628 ( 2 )

Abstract:


In drug discovery, a hit series, with the desired primary and secondary activities, as well as physiochemical properties is identified such that the final agent will be useful when administered to real patients [1]. Medicinal chemistry can improve recognition and the binding geometries (pharmacophores) of candidate compounds, and their target’s affinity. Medicinal chemistry, in a modern view, is dedicated to understanding molecular mechanisms, chemical relationships, and the pharmacological activities involved in drug action thru pharmacodynamic and pharmacokinetic factors. The introduction of new technologies has become a prime concept in medicinal chemistry, expanding its interdisciplinary character. Most drugs are small bioactive molecules that interact with specific macromolecules or receptors, resulting in therapeutic effects. Modern computational methods determine...

Editorial:, Research, and, Selection, of, Multitarget, Compounds, in, Medicinal, Chemistry

Affiliation:

Federal University of Paraíba Campus I, 58051-900, João Pessoa-PB, State University of Paraiba Biological Science Department Laboratory of Synthesis and Drug Delivery, Campus V 58070-450, João Pessoa, PB, Federal University of Paraíba Campus I, 58051-900, João Pessoa-PB



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