Call for Papers  

Article Details


Syntheses, Transformations and Pharmaceutical Applications of Kynurenic Acid Derivatives

[ Vol. 16 , Issue. 36 ]

Author(s):

F. Fulop, I. Szatmari, E. Vamos, D. Zadori, J. Toldi and L. Vecsei   Pages 4828 - 4842 ( 15 )

Abstract:


The syntheses and transformations of 4-hydroxyquinoline-2-carboxylic acid, kynurenic acid, are reviewed, and special attention is paid to the pharmacological activities and pharmaceutical applications of its derivatives.

Keywords:

Kynurenic acid,kynurenic acid derivatives,neurological disorders,schizophrenia,retinal damage,diabetes mellitus,hypertension

Affiliation:

, , , , , Institute of Pharmaceutical Chemistry and Research Group for Stereochemistry, Hungarian Academy of Sciences, University of Szeged, H-6720 Szeged, Eotvos u. 6, Hungary.



Read Full-Text article