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Honey: An Effective Regenerative Medicine Product in Wound Management

[ Vol. 26 , Issue. 27 ]

Author(s):

Simona Martinotti*, Marcela Bucekova , Juraj Majtan and Elia Ranzato   Pages 5230 - 5240 ( 11 )

Abstract:


Honey has successfully been used in the treatment of a broad spectrum of injuries including burns and non-healing wounds. It acts as an antibacterial and anti-biofilm agent with anti/pro-inflammatory properties. However, besides these traditional properties, recent evidence suggests that honey is also an immunomodulator in wound healing and contains several bee and plant-derived components that may speed up wound healing and tissue regeneration process. Identifying their exact mechanism of action allows better understanding of honey healing properties and promotes its wider translation into clinical practice.

This review will discuss the physiological basis for the use of honey in wound management, its current clinical uses, as well as the potential role of honey bioactive compounds in dermal regenerative medicine and tissue re-modeling.

Keywords:

Honey, wound repair, regenerative medicine, tissue, immunomodulator, wound healing.

Affiliation:

DiSIT-Dipartimento di Scienze e Innovazione Tecnologica, University of Piemonte Orientale, Viale Teresa Michel 11, Alessandria, 15121, Laboratory of Apidology and Apitherapy, Institute of Molecular Biology, Slovak Academy of Sciences, Dubravska cesta 21, 845 51, Bratislava, Laboratory of Apidology and Apitherapy, Institute of Molecular Biology, Slovak Academy of Sciences, Dubravska cesta 21, 845 51, Bratislava, DiSIT-Dipartimento di Scienze e Innovazione Tecnologica, University of Piemonte Orientale, Piazza Sant'Eusebio 5, Vercelli, 13100



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