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Betulin-Betulinic Acid Natural Product Based Analogs as Anti-Cancer Agents

[ Vol. 13 , Issue. 10 ]

Author(s):

Subash C. Jonnalagadda, Michael A. Corsello and Christopher E. Sleet   Pages 1477 - 1499 ( 23 )

Abstract:


Herein we describe a brief account of betulin and betulinic acid: two natural products isolated from birch bark, their chemical modifications and further biological/medicinal applications.

Keywords:

Natural products, terpenes, lupanes, triterpenoids, birch bark, betulin, betulinic acid, anti-cancer agents.

Affiliation:

, , Department of Chemistry and Biochemistry, Rowan University, Glassboro, NJ 08028, USA.



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