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Gene Regulation in Cancer Gene Therapy Strategies

[ Vol. 10 , Issue. 20 ]


Ian Scanlon, Panos Lehouritis, Ion Niculescu-Duvaz, Richard Marais and Caroline J. Springer   Pages 2175 - 2184 ( 10 )


Regulation of expression in gene therapy is considered to be a very desirable goal, preventing toxic effects and improving biological efficacy. A variety of systems have been reported in an ever widening range of applications, this paper describes these systems with specific reference to cancer gene therapy.


transcriptional control, regulated expression, gdept, suicide gene


Cancer Research UK Centre for Cancer Therapeutics at the Institute of Cancer Research, 15Cotswold Road, Sutton, Surrey, SM2 5NG; UK

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