Tatiana Da Ros, Giampiero Spalluto, Maurizio Prato, Tula Saison-Behmoaras, Alexandre Boutorine and Barbara Cacciari Pages 71 - 88 ( 18 )
In this account we summarise recent studies on oligonucleotides and oligonucleotide derivatives and their utilisation in antigene, antisense and decoy approaches, with particular attention to peptide nucleic acids, locked nucleic acids and oligonucleotide conjugates, the most promising compounds in this field.
antisense oligonucleotides,mrna,Rnase,hybridisation,gene-directed therapy
, , , , , Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa.