Shoei-Sheng Lee and Wen-Liang Chang Pages 1461 - 1477 ( 17 )
Cytotoxic natural products isolated from Formosan plants and marine organisms till December, 2002, by local scientists or Taiwanese researchers have been reviewed. A total of about 200 compounds belonging to six types of chemical structures are listed or / and described in this article. Several compounds with special or selective activity have been described in more details. Some structure-activity relationships for the compounds of the same skeleton are drawn to clarify the possible pharmacophores.
cytotoxicity,formosan plants,marine organisms,in vitro assay,structural properties
, School of Pharmacy,College of Medicine, National Taiwan University, 1 Jen-Ai Rd., Sec. 1,Taipei 100, Taiwan, China