Laszlo Orfi, Frigyes Waczek, Janos Pato, Istvan Varga, Balint Hegymegi-Barakonyi, Richard A. Houghten and Gyorgy Ker Pages 2549 - 2553 ( 5 )
Purine bases and their bioisosteric analogs are widely used as building blocks in combinatorial chemistry. Recently a great number of fused pyrimidine derivatives became known as potential drug molecules against various types of proliferative diseases, caused by over-expression of protein kinases [1]. One of the most important compound
pyrimidines,quinazolin-4-ones,formamidine-acetate,imidoyl-chlorides,purine analogs,protein kinase inhibitors,antiproliferative agents,phosphodiesterase v inhibitors
, , , , , , Department of Pharmaceutical Chemistry, Semmelweis University, Hogyes E. u. 9, Budapest, Hungary.