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Endoplasmic Stress Inhibitors for Homocysteine Induced Cardiovascular Disease

[ Vol. 22 , Issue. 18 ]

Author(s):

Anthony Zulli   Pages 2704 - 2708 ( 5 )

Abstract:


Cardiovascular disease (CVD) remains a major cause of death and disability worldwide, thus preventing and inhibiting CVD remains a health priority. Several lines of pharmacological interventions have not met with great success, thus inhibition of novel cellular stress pathways could be a novel therapeutic avenue to treat CVD. This review will focus on homocysteine and endoplasmic reticulum stress linked to mitochondria function, and possible therapeutic avenues for treatment.

Keywords:

Endoplasmic reticulum stress, endothelial function, homocysteine, atherosclerosis, taurine, Nox.

Affiliation:

College of Health and Biomedicine, Victoria University, St. Albans, Autstralia.



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