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Review Article

Advances of Phenoxazines: Synthesis, Reactivity and Their Medicinal Applications

[ Vol. 23 , Issue. 26 ]


Sotirios Katsamakas, Alexandros L. Zografos and Vasiliki Sarli   Pages 2972 - 2999 ( 28 )


Phenoxazines are an important class of heterocycles, which are emerging in the field of medicinal chemistry. They exhibit numerous biological activities, including antiviral, anticancer, anti-Alzheimer, antidiabetic, antioxidant, anti-inflammatory, antibiotic and many more. The present review focuses on the chemistry along with the medicinal applications of the phenoxazine moiety, in order to provide a greater insight for the development of future phenoxazine therapeutics.


Phenoxazines, actinomycin, phenoxazine synthesis, phenoxazine biosynthesis, phenoxazine applications, phenoxazine bioactivities, phenoxazine natural products.


, , Department of Chemistry, Aristotle University of Thessaloniki, University Campus, Thessaloniki 54124, Greece.

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