Rajendra Pawar, Ariella Shikanov, Boris Vaisman and Abraham J. Domb Pages 397 - 402 ( 6 )
Paclitaxel has been proven to be effective against different types of cancer. A delivery system loaded with paclitaxel at tumor site should provide a high local concentration of the drug detrimental to malignant cells, which prevents the re-growth and metastasis of tumor. In this review, paclitaxel formulations for systemic and for intratumoral administration are discussed.
paclitaxel,delivery systems,polymers,intratumoral delivery,formulations
, , , Department of Medicinal Chemistry and Natural Products, The Hebrew University, School ofPharmacy-Faculty of Medicine, Jerusalem 91120, Israel.