Ian Scanlon, Panos Lehouritis, Ion Niculescu-Duvaz, Richard Marais and Caroline J. Springer Pages 2175 - 2184 ( 10 )
Regulation of expression in gene therapy is considered to be a very desirable goal, preventing toxic effects and improving biological efficacy. A variety of systems have been reported in an ever widening range of applications, this paper describes these systems with specific reference to cancer gene therapy.
transcriptional control,regulated expression,gdept,suicide gene
, , , , Cancer Research UK Centre for Cancer Therapeutics at the Institute of Cancer Research, 15Cotswold Road, Sutton, Surrey, SM2 5NG; UK