Brooke Lustig and Kuan-Teh Jeang Pages 1181 - 1187 ( 7 )
Ribozymes are catalytic RNAs that can cleave substrate RNAs in a sequence specific manner. Here we survey, in brief, the structure of hammerhead and hairpin ribozymes and discuss their applications as molecular antiviral molecules for HIV-1.
Hammerhead Ribozymes,Anti-viral Molecules,RIBOZYMES,HAMMERHEAD RIBOZYME
, Department of Chemistry 1,San Jose State University, San Jose, CA 95192 and Laboratory ofMolecular Microbiology, National Institute of Allergy and InfectiousDiseases, Bethesda, MD 20892-0460, USA