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Review Article

LINC00667: A Novel Vital Oncogenic LincRNA

Author(s):

Yaqi Hu, Yifan Zhang, Shuwen Wang, Rui Wang, Qi Yuan, Leiqi Zhu, Fangqi Xia, Mengzhen Xue, Yaqi Wang, Yuanyang Li and Chengfu Yuan*   Pages 1 - 10 ( 10 )

Abstract:


Long intergenic noncoding RNAs (lincRNAs) have a variety of properties that differ from those of messenger RNAs (mRNAs) encoding proteins. Long intergenic nonprotein coding RNA 667 (LINC00667) is a non-coding transcript located on chromosome 18p11.31. Recently, many studies have found that LINC00667 can enhance the progression of various cancers and play a key part in a lot of diseases, such as tumorigenesis. Therefore, LINC00667 can be recognized as a potential biomarker and therapeutic target. So, we reviewed the biological functions, relevant mechanisms, as well as clinical significance of LINC00667 in several human cancers in detail.

Keywords:

LINC00667,long intergenic noncoding RNAs (lincRNAs),cancers,cell functions

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