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Another look at dietary polyphenols: challenges in cancer prevention and treatment

Author(s):

Roberto Arrigoni, Andrea Ballini*, Luigi Santacroce , Stefania Cantore, Angelo Inchingolo, Francesco Inchingolo , Marina Di Domenico , Lucio Quagliuolo and Mariarosaria Boccellino  

Abstract:


Cancer is a pathology that impacts in a profound manner people all over the world. The election strategy against cancer often uses chemotherapy and radiotherapy, which more often than not can present many side effects and not always reliable efficacy. By contrast, it is widely known that a diet rich in fruit and vegetables has a protective effect against cancer insurgence and development. Polyphenols are generally believed to be responsible for those beneficial actions, at least partially. In this review, we highlight the metabolic interaction between polyphenols and our metabolism and discuss their potential for anticancer prevention and therapy.

Keywords:

cancer, biological chemistry, chemoprevention, dietary antioxidants, clinical biochemistry and clinical molecular biology, polyphenols, clinical microbiology, translational medicine.

Affiliation:

CNR Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), 70124 Bari, Department of Biosciences, Biotechnologies and Biopharmaceutics, Campus Universitario “Ernesto Quagliariello”, University of Bari "Aldo Moro", 70125 Bari, Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", 70124 Bari, Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", 70124 Bari, Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", 70124 Bari, Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", 70124 Bari, Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples



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