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Review Article

Synthesis, Biological Activity and Medicinal Applications of Ruthenium Complexes Containing Carbohydrate Ligands

[ Vol. 26 , Issue. 35 ]

Author(s):

Ana Cristina Fernandes*   Pages 6412 - 6437 ( 26 )

Abstract:


The search for new metal-efficient drugs has attracted considerable attention of the scientific community. Among them, ruthenium complexes have emerged as an excellent alternative of platinum complexes. This review presents a thorough and timely coverage of the synthesis, biological activity and medicinal applications of ruthenium complexes bearing carbohydrate ligands, allowing a large community of readers, in particularly the community that works in organic, inorganic, bioorganometallic and medicinal chemistry, ready access to the most relevant examples.

Keywords:

Ruthenium, carbohydrates, nucleolipidic complexes, polypyridyl complexes, arene complexes, cyclopentadienyl complexes, tricarbonyl complexes.

Affiliation:

Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049- 001 Lisboa



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