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Review Article

Nanostructured Calcium-based Biomaterials and their Application in Drug Delivery

[ Vol. 27 , Issue. 31 ]

Author(s):

Li-Juan Yi, Jun-Feng Li*, Ming-Guo Ma* and Ying-Jie Zhu*   Pages 5189 - 5212 ( 24 )

Abstract:


In the past several decades, various types of nanostructured biomaterials have been developed. These nanostructured biomaterials have promising applications in biomedical fields such as bone repair, tissue engineering, drug delivery, gene delivery, antibacterial agents, and bioimaging. Nanostructured biomaterials with high biocompatibility, including calcium phosphate, hydroxyapatite, and calcium silicate, are ideal candidates for drug delivery. This review article is not intended to offer a comprehensive review of the nanostructured biomaterials and their application in drug delivery but rather presents a brief summary of the recent progress in this field. Our recent endeavors in the research of nanostructured biomaterials for drug delivery are also summarized. Special attention is paid to the synthesis and properties of nanostructured biomaterials and their application in drug delivery with the use of typical examples. Finally, we discuss the problems and future perspectives of nanostructured biomaterials in the drug delivery field.

Keywords:

Biomaterials, nanostructure, drug delivery, synthesis, properties, applications.

Affiliation:

Key Laboratory for Green Process of Chemical Engineering of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering, Shihezi University, Shihezi 832003, College of Water Conservancy and Architectural Engineering, Shihezi University, Shihezi, Xinjiang, 832000, Key Laboratory for Green Process of Chemical Engineering of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering, Shihezi University, Shihezi 832003, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050



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